Gene Expression Omnibus (GEO)
نویسنده
چکیده
The Gene Expression Omnibus (GEO) is an international public repository that archives and freely distributes microarray, next-generation sequencing, and other forms of highthroughput functional genomic data sets (1). Approximately 90% of the data in GEO are gene expression studies that investigate a broad range of biological themes including disease, development, evolution, immunity, ecology, toxicology, metabolism, and more. The non-expression data in GEO represent other categories of functional genomic and epigenomic studies including those that examine genome methylation, chromatin structure, genome copy number variations, and genome–protein interactions. A breakdown of GEO data types and technologies is provided on the repository Summary page.
منابع مشابه
Gene Expression Profile Analysis during Mouse Tooth Development
Introduction: Complex molecular pathways involve in development of different tissues such as teeth. Differential gene expression patterns during teeth development generates different tooth types. Teeth development results from interactions between oral epithelium and underlying ectomesenchyme cells with neural crest origin. Teeth development are regulated by different signaling networks. In thi...
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The Gene Expression Omnibus (GEO) project was initiated at NCBI in 1999 in response to the growing demand for a public repository for data generated from high-throughput microarray experiments. GEO has a flexible and open design that allows the submission, storage, and retrieval of many types of data sets, such as those from high-throughput gene expression, genomic hybridization, and antibody a...
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The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data. GEO provides a flexible and open design that facilitates submission, storage and retrieval of heterogeneous data sets from high-throughput gene expression and genomic hybridization experiments. GEO is not intended to replace in house gene ex...
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Background & Aims: The use of siRNA to silence gene expression is increasingly expanding today. The aim of this study is to bioinformatically and experimentally investigate the inhibition of the HMGA2 gene and its corresponding effects on downstream genes expression rate in MDA-MB-231 cancer cell treated by shRNA and siRNA specific to HMGA2. Materials & Methods: To perform this bioinformatic a...
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The Gene Expression Omnibus (GEO) repository at the National Center for Biotechnology Information (NCBI) archives and freely disseminates microarray and other forms of high-throughput data generated by the scientific community. The database has a minimum information about a microarray experiment (MIAME)-compliant infrastructure that captures fully annotated raw and processed data. Several data ...
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